Paxil- Antidepressants that May Prevent Heart Failure
Paroxetine is a generic name for Paxil. It is a prescribed medication that treats depression and other problems like obsessive-compulsive disorder, panic disorder, and post traumatic syndrome and social anxiety. Furthermore, this drug is also used for premenstrual dysphoric disorder that includes physical and psychological problems before the onset of menstrual period of a woman. It can also be used in headaches, and tingling sensation of the feet and hands that are caused by the disease called diabetes.
Paroxetine (Paxil) is considered as one of the most effective drug ans a selective serotonin reuptake inhibitor. This drug works by preventing some receptors in the the the human brain from reabsorbing serotonin. Serotonin function is to help individuals to be mentally stable. Paxil helps to maintain the mental equilibrium of every individual and alleviate some negative feelings. In addition to this, it can help the person with heart failure to increased the myocardial contractility.
On the other hand, some researches done by John Tesmer, a professor in U-M Life Sciences Institute found out that Paxil inhibits the action of the G protein receptor kinase, it is over expressed when people have heart failure. Furthermore, they published a research paper with Paroxetine as a direct inhibitor of the G protein receptor kinase that increase the ability of the myocardium to contract. Paroxetine found out to be effective in their study with the animal model. Researches of this study really believes that they can continue this until they attain therapeutic levels.